GenomeQuest Industry » ChIP-Seq http://blog.genomequest.com Conversations on the convergence of SDM, cloud computing, and applications to personalized medicine Thu, 12 Jan 2012 23:33:19 +0000 http://wordpress.org/?v=2.9.2 en hourly 1 Announcing ChIP-Seq Support http://blog.genomequest.com/2009/11/announcing-chip-seq-support/ http://blog.genomequest.com/2009/11/announcing-chip-seq-support/#comments Mon, 09 Nov 2009 13:30:19 +0000 GenomeQuest http://blog.genomequest.com/?p=75 We’ve released our ChIP-Seq workflow this week, available to anyone with a Free Basic Account inside of GenomeQuest. Like all of our NGS workflows, it runs in two basic steps: a mapping step and a downstream analysis step. In this case, of course, the downstream analysis is a peak-finding algorithm. We chose the MACS modeling software for peak modeling. (You can see the entire workflow’s documentation here.) Integrated into the GenomeQuest Sequence Data Management platform, it outputs a heavily annotated sequence database, which can then be interactively filtered, grouped, sorted, and mined for peaks of interest. And this can all be connected to your RNA-Seq and resequencing data to get the global picture.

So now researchers can go from their ChIP-Seq NGS runs directly to gene-based annotation of the peaks found by their biology. Select regions of interest, or genes of interest, or peaks of a certain class, and drill down to see the actual evidence that backs up the call.

We’re giving away free ChIP-Seq runs to the first 100 people to sign up.

As always, feel free to leave a comment – we read every one.

Richard J. Resnick
VP Software and Services

]]> http://blog.genomequest.com/2009/11/announcing-chip-seq-support/feed/ 0