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NYT: Super-Computers Altering Science

Yes, Moore's Law is generating amazing hand devices but it's also powering the next generation of science.  As John Markoff says, so much so that the best researchers are framing big questions so that super-computers can work on big answers.  Nowhere is this more true than in comparative genomics where we're ...

JAMA Editorial: “Immediate Effect” of Whole Genome Sequencing on Cancer Treatment

The April 20, 2011 issue of the Journal of the American Medical Association, includes an editorial that speaks of the "remarkable" power of genomics for diagnosis of cancer.  Citing two patient examples, it argues that fundamental advances in cost and speed of whole-genome sequencing will likely make personalized genomic medicine for cancer treatment commonplace in ...

Whole genome MDx — a significant step forward for health care?

Last week, GenomeQuest announced whole-genome diagnostics reporting -- I thought that I'd offer some product and industry perspective on this news. The wonderful genetic experts at GeneTests have collected global research on over 2000 genetic disorders – GenomeQuest has built that database into its sequence analysis platform.  From a single, whole-genome sequence ...

Join us at World Health Forum for Major Announcement

Join us at World Health Forum for announcement on collaboration with Harvard hospital re: pathology application of personalized (molecular) medicine: http://bit.ly/9te2En . Exciting to be a part of genomics arcing to ...

The Economist on “Biology 2.0″

Good to see reasonably positive/researched/balanced reporting on genomics in a mainstream publication: http://www.economist.com/node/16349358?story_id=16349358.  I believe that the public getting educated/excited about genomics-driven personalized medicine will accelerate the genomics "arc to clinical" -- a good thing, I think, for the life science community and the public at large. Some excerpts: ... the science of biology is ...

Good Crowd at GQ Harvard Seminar

Last week, GenomeQuest held our "The Next Generation of Sequence Analysis" seminar for Harvard-based Researchers.  It was sponsored by Bob Steen, manager of the Harvard Biopolymers Facility. According to Bob, it was the 2nd largest crowd ever for his seminars and the largest ever for a software topic -- an indicator that reseachers ...

Research Using Next Generation Sequencing: Moving from “Information Bottleneck” to “Information Renaissance”

This week, I attended the Consumer Genomics Show (more so a “clinical genomics" show). In a session on Next Generation Sequencing led by five industry experts, a recurring observation was that, on the one hand, steady investments in sequencing technology was indeed delivering breathtaking value and driving down sequencing costs – bravo indeed and ...

A Responsibility to Leverage the Leadership and Investments of NIH

Despite understandably varied opinions on the US federal government, I think that most of us can agree that U.S. National Institute of Health (NIH) has done remarkable things for the world and life sciences. They are the world driver and biggest supporter of genetic research, they largely funded the $3B Human Genome Project, and ...

Perhaps the Biggest (Unintended) Consequence to the Health Care Bill

The most thoughtful folks in the health care industry acknowledge that the future will be defined by molecular (aka personalized) medicine. Without being infinitely tedious, it will be a matter of measuring your body's instructions (DNA) and your present state (RNA/proteins) and prescribing a course of treatment with the most likely positive outcome and ...