Archive by Author

Fixing Healthcare Requires Patience

The provocative title The Debt Crisis and the Human Genome belies Mike Mandels underlying message. I do worry that articles like this and the recent NY Times article A Decade Later, Human Genome Project Yields Few New Cures feed the cynics. Our society is so enamored with immediate gratification. Rome wasn't built in ...

Gene patents on trial II

Following an earlier post, the ruling by the federal judge 0n the BRCA patents held by Myriad has created a firestorm of controversy in the blogs and in the popular media. Check this out!: NPR: Gene Ruling Could Have Wide Implications 60 Minutes: Gene Patents The industry blog Genetic Future has sponsored an ...

Industry confusing “Cloud” with “Infrastructure”

Earlier I blogged on the distinctions between Infrastructure, Platform, and Software-as-a-Service offerings. The message was that "cloud" is an overloaded word and takes many forms and has different customer value propositions. A recent commentary in GenomeWeb "Considering a Cloud? Cost isn't everything..." citing the paper "The Real Cost of a CPU Hour" ...

Consumer genomics in NY Times

GenomeQuest could have  targeted consumers, the largest available market for its technology. When we entered the market in 2004, the consumer wave was a distant vision, not even on the horizon. How did we survive? We targeted the smallest segment we could find: Information Scientists and Biotech Patent Lawyers. Why? My father was a old-school ...

MassDevice: Ethics of Personal Genomes

Brad Perriello at MassDevice interviewed me and posted the article in their popular e-newsletter on the medical device industry. You can read the interview here. Brad caught me a little off guard when he asked me what I considered to be the ethical implications of individuals having access to their genomes. In a couple ...

Small step for Personalized Medicine

An article by Nicholas Wade, science writer for the New York Times Disease Cause Is Pinpointed With Genome describes two research teams who have independently sequenced the entire genome of patients to find the exact genetic cause of their diseases. A fantastic research blog post at Genetic Future titled Disease hunting ...

Next-Gen Sequencing in 2010

Brilliant analytical overview of Next-Generation Sequencing machines compiled by Dan Koboldt at MassGenomics from the recent AGBT event in Marco Island. And another by Boonsri Dickinson at SmartPlanet The amazing race for the cheapest and fastest DNA machine.

Developers Wanted

Today, we launched our API’s for Sequence Data Management on the cloud. So what? GenomeQuest is now for bioinformatics and computational biologists (we call them developers for short). These are people who prefer to write code in Unix, and prefer awk, perl, and sed to Firefox, Internet Explorer, Safari, or Chrome. So why is that important? With no ...

An SDM Cloud?

Executives in the industry sometimes ask me if we are moving our software to the “cloud”. When I say we are already a cloud, then they wonder: “then what is Amazon offering?” Its helpful to think of the cloud as a layered architecture. The VC Bessemer provides a nice definition of this layering. Infrastructure-as-a-Service: Web-services ...

“Watson meets Moore”

The title of the article on the new $50,000 ION Torrent machine by Kevin Davies at Bio-IT World says it all: "Watson meets Moore" as Ion Torrent Introduces Semiconductor Sequencing