Archive | January, 2010

Programming the cloud

If you are a developer or a technical type, this one is for you. Over at Depth-First there is a blog post about an application in the cheminformatics field: PubCouch: Streams aren't just for Pipeline Pilot. The author illustrates how a well abstracted Web service avoids the costly database Extract-Transform-Load operations so familiar ...

So, what’s the argument for cloud computing?

A plot of the Evolution of Computer Capacity and Costs shows that compute power will be 1,000X cheaper in 10 years. How much lower can it go? As this happens the relative cost of managing another computer goes asymptotic to zero, regardless of whether its hosted internally or externally. I don't think there is ...

Challenges in 1000 Genomes Data

Variant reports are not the right deliverable for a re-sequencing study. A well written technical blog 'MassGenomics' written by Dan Koboldt illustrates why. Dan says "What’s more, with the advent of next-generation sequencing, I hate to tell you, but people are going to be reporting a lot of false positives.  I guarantee it.  So when ...